Ceruloplasmin Antikörper (AA 20-259)

Produktnummer ABIN3044507

Der Kaninchen Polyklonal Anti-Ceruloplasmin Antikörper wurde für WB und FACS validiert. Er ist geeignet, Ceruloplasmin in Proben von Human zu detektieren.

Kurzübersicht für Ceruloplasmin Antikörper (AA 20-259) (ABIN3044507)

Target: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ceruloplasmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-Ceruloplasmin Antikörper

Bindungsspezifität: AA 20-259

Verwendungszweck: Anti-Ceruloplasmin/CP Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Ceruloplasmin(CP) detection. Tested with WB, IHC-P in Human.Protein Name: Ceruloplasmin

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Ceruloplasmin recombinant protein (Position: K20-M259). Human Ceruloplasmin shares 80.8% and 79.6% amino acid (aa) sequence identity with mouse and rat Ceruloplasmin, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu Ceruloplasmin

Target: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Andere Bezeichnung: CP

Hintergrund:

Synonyms: Ceruloplasmin;1.16.3.1;Ferroxidase;CP;

Tissue Specificity: Expressed by the liver and secreted in plasma.

Background: Ceruloplasmin  (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II)transferrin to Fe (III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Molekulargewicht: 122 kDa

Gen-ID: 1356

UniProt: P00450

Pathways: Transition Metal Ion Homeostasis