MCM5 Antikörper (C-Term)

Produktnummer ABIN3044244

Produktdetails anti-MCM5 Antikörper

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Bindungsspezifität: AA 720-734, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM5(MCM5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: EIQHRMQRKV LYRLK

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM5(MCM5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: minichromosome maintenance complex component 5
Protein Name: DNA replication licensing factor MCM5

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MCM5(720-734aa EIQHRMQRKVLYRLK), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MCM5

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Andere Bezeichnung: MCM5 (MCM5 Produkte)

Synonyme: 23.m06024 antikoerper, cdc46 antikoerper, xmcm5 antikoerper, CDC46 antikoerper, P1-CDC46 antikoerper, Afu5g02520 antikoerper, NCU01171.1 antikoerper, AA617332 antikoerper, AI324988 antikoerper, AL033333 antikoerper, Cdc46 antikoerper, Mcmd5 antikoerper, mCD46 antikoerper, mCDC46 antikoerper, mcm5 antikoerper, wu:fb34a06 antikoerper, CG4082 antikoerper, DmCDC46 antikoerper, DmCDC465 antikoerper, DmMCM5 antikoerper, DmMcm5 antikoerper, DmeMCM5 antikoerper, Dmel\\CG4082 antikoerper, MCM5 antikoerper, McM5 antikoerper, PCR4 antikoerper, DNA replication licensing factor MCM5 antikoerper, minichromosome maintenance complex component 5 S homeolog antikoerper, minichromosome maintenance complex component 5 antikoerper, DNA replication licensing factor Mcm5 antikoerper, DNA replication licensing factor mcm5 antikoerper, MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) antikoerper, minichromosome maintenance complex component 5 L homeolog antikoerper, Minichromosome maintenance 5 antikoerper, DNA replication licensing factor mcm-5 antikoerper, BBOV_IV010040 antikoerper, mcm5.S antikoerper, MCM5 antikoerper, AFUA_5G02520 antikoerper, NCU01171 antikoerper, PVX_084615 antikoerper, LOC5576119 antikoerper, CpipJ_CPIJ008678 antikoerper, Bm1_24480 antikoerper, CMU_022890 antikoerper, Mcm5 antikoerper, mcm5 antikoerper, TP01_0722 antikoerper, mcm5.L antikoerper, mcm-5 antikoerper

Hintergrund: MCM5(MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 5),also known as CDC46, is a protein that in humans is encoded by the MCM5 gene. MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. And MCM5 is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The MCM5 gene is mapped on 22q12.3. The MCM5 gene contains 16 exons. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Synonyms: CDC 46 antibody|CDC46 antibody|CDC46 homolog antibody|Cell division cycle 46 antibody|DNA replication licensing factor antibody|DNA replication licensing factor MCM 5 antibody|DNA replication licensing factor MCM5 antibody|MCM 5 antibody|MCM5 antibody|MCM5_HUMAN antibody|MGC5315 antibody|Minichromosome maintenance complex component 5 antibody|Minichromosome maintenance deficient(S. cerevisiae) 5 antibody|Minichromosome maintenance deficient 5 antibody|Minichromosome maintenance deficient protein 5 antibody|P1 CDC46 antibody|P1-CDC46 antibody

UniProt: P33992

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA