SOD3 Antikörper (N-Term)

Produktnummer ABIN3044113

Produktdetails anti-SOD3 Antikörper

Target: SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

Bindungsspezifität: AA 41-56, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Rabbit IgG polyclonal antibody for Extracellular superoxide dismutase[Cu-Zn](SOD3) detection. Tested with WB, IHC-P, IHC-F, ICC in Human.

Sequenz: KVTEIWQEVM QRRDDD

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Extracellular superoxide dismutase[Cu-Zn](SOD3) detection. Tested with WB, IHC-P, IHC-F, ICC in Human.
Gene Name: superoxide dismutase 3, extracellular
Protein Name: Extracellular superoxide dismutase[Cu-Zn]

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SOD3 (41-56aa KVTEIWQEVMQRRDDD).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-SOD3 Antikörper (ABIN3044113)

Li, Xiao, Li, Li, Zeng, Liu, Liang, Li, Chu, Yang: "Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1715-1722, (2018) (PubMed).

Wu, Ming, Zhang, Wu, Wu, Yao: "Edaravone rescues the lung by inhibiting lipid peroxidation and pro-inflammatory cytokines in a rat model." in: Chinese medical journal, Vol. 127, Issue 5, pp. 968-70, (2014) (PubMed).

Details zu SOD3

Target: SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

Andere Bezeichnung: SOD3 (SOD3 Produkte)

Synonyme: EC-SOD antikoerper, ECSOD antikoerper, SOD3 antikoerper, AI314465 antikoerper, LOC780439 antikoerper, fb05f10 antikoerper, si:dkey-117m1.6 antikoerper, sod3 antikoerper, wu:fb05f10 antikoerper, ECSODPT antikoerper, CuZnSOD antikoerper, SODA.4 antikoerper, superoxide dismutase 3 antikoerper, superoxide dismutase 3, extracellular antikoerper, superoxide dismutase 3, extracellular b antikoerper, superoxide dismutase 1 antikoerper, superoxide dismutase precursor ,putative antikoerper, SOD3 antikoerper, Sod3 antikoerper, sod3b antikoerper, sod3 antikoerper, Sod1 antikoerper, Smp_095980 antikoerper

Hintergrund: SOD3(SUPEROXIDE DISMUTASE 3) also called SUPEROXIDE DISMUTASE, EXTRACELLULAR, EC-SOD, and Cu-Zn, is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. Hendrickson et al.(1990) mapped the SOD3 gene to 4pter-q21 by a study of somatic cell hybrids. Stern et al.(2003) narrowed the assignment to 4p15.3-p15.1 by somatic cell and radiation hybrid analysis, linkage mapping, and FISH. The product of this gene is though to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix(ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.

Synonyms: EC SOD antibody|EC-SOD antibody|Extracellular superoxide dismutase[Cu Zn] antibody|Extracellular superoxide dismutase[Cu-Zn] antibody|Extracellular superoxide dismutase antibody|Extracellular superoxide dismutase precursor antibody|MGC20077 antibody|SOD 3 antibody|SOD3 antibody|SODE_HUMAN antibody|Superoxide dismutase 3 extracellular antibody

UniProt: P08294