SOD3 Antikörper (N-Term)

Produktnummer ABIN390857

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-SOD3 Antikörper wird verwendet zum Nachweis von SOD3 in Proben von Human. Er wurde validiert für WB, FACS und IHC (p).

Kurzübersicht für SOD3 Antikörper (N-Term) (ABIN390857)

Target: SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB19866

Produktdetails anti-SOD3 Antikörper

Bindungsspezifität: AA 7-36, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SOD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human SOD3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-SOD3 Antikörper (ABIN390857)

Kannan, Nguyen, Makarem, Dong, Shih, Eirew, Raouf, Emerman, Eaves: "Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7789-94, (2014) (PubMed).

Details zu SOD3

Target: SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

Andere Bezeichnung: SOD3

Hintergrund: SOD3 is a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. This protein is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.

Molekulargewicht: 25851

Gen-ID: 6649

NCBI Accession: NP_003093

UniProt: P08294