SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 253-267), (C-Term) Antikörper

Details zu Produkt Nr. ABIN3043979
Antigen
  • MLP
  • Xmad1
  • Xsmad1
  • bsp1
  • jv4-1
  • jv41
  • madh1
  • madr1
  • smad-1
  • MADH1
  • fb39h09
  • wu:fb39h09
  • wu:fb97e04
  • 2/23
  • CG12399
  • Dmel\\CG12399
  • E(zen)2
  • En(vvl)
  • MAD
  • Mat
  • P-Mad
  • P-mad
  • PMad
  • Smad
  • Smad1
  • apg
  • c28
  • dMAD
  • dMad
  • l(2)K00237
  • l(2)k00237
  • mad
  • p-Mad
  • pMAD
  • pMad
  • pSmad
  • BSP-1
  • BSP1
  • JV4-1
  • JV41
  • MADR1
  • AI528653
  • Madh1
  • Madr1
  • Mlp1
  • MusMLP
  • smad1
  • xmad
  • SMAD family member 1
  • Mothers against dpp
  • SMAD family member 1 L homeolog
  • smad1
  • SMAD1
  • Mad
  • Smad1
  • smad1.L
Epitop
AA 253-267, C-Term
57
27
24
20
18
16
12
10
10
8
8
7
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Ratte (Rattus)
362
239
201
14
12
11
11
10
9
8
7
6
6
6
4
3
2
2
2
2
2
2
2
2
1
Wirt
Kaninchen
343
43
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
21
11
9
9
9
9
9
9
7
2
2
2
2
2
2
2
2
Applikation
Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
300
151
110
46
44
26
25
25
14
8
5
4
3
2
1
1
1
1
1
Optionen
Verwendungszweck Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 1(SMAD1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of mouse Smad1(253-267aa AEISRGDVQAVAYEE), different from the related rat sequence by one amino acid, and different from the related human sequence by two amino acids.
Sequenz AEISRGDVQA VAYEE
Isotyp IgG
Kreuzreaktivität (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Produktmerkmale Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 1(SMAD1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: SMAD family member 1
Protein Name: Mothers against decapentaplegic homolog 1
Reinigung Immunogen affinity purified.
Antigen
Andere Bezeichnung SMAD1 (SMAD1 Antibody Abstract)
Hintergrund Mothers against decapentaplegic homolog 1 also known as SMAD family member 1 or SMAD1 is a protein that in humans is encoded by the SMAD1 gene. SMAD1 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene "mothers against decapentaplegic"(Mad) and the C. elegans gene Sma. The gene was assigned to human chromosome 4q31.21. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.

Synonyms: BSP-1 antibody|BSP1 antibody|Dwarfin A antibody|DwfA antibody|HsMAD1 antibody|JV4 1 antibody|JV4-1 antibody|JV41 antibody|MAD homolog 1 antibody|MAD mothers against decapentaplegic homolog 1 antibody|Mad related protein 1 antibody|Mad-related protein 1 antibody|MADH1 antibody|Madr 1 antibody|MADR1 antibody|Mothers against decapentaplegic homolog 1 antibody|Mothers against DPP homolog 1 antibody|SMA- AND MAD-RELATED PROTEIN 1 antibody|SMAD 1 antibody|SMAD family member 1 antibody|SMAD mothers against DPP homolog 1 antibody|SMAD mothers against DPP homolog 1 Drosophila antibody|Smad1 antibody|SMAD1_HUMAN antibody|Spinal muscular atrophy distal with upper limb predominance antibody|TGF beta signaling protein 1 antibody|Transforming growth factor beta signaling protein 1 antibody|Transforming growth factor-beta-signaling protein 1 antibody
UniProt P70340
Pathways Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Applikations-hinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for SMAD1 is approximately 30 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Konservierungs-mittel Thimerosal (Merthiolate), Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Haltbarkeit 12 months
Bilder des Herstellers
Image no. 1 for anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 253-267), (C-Term) antibody (ABIN3043979) Anti-Smad1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue
Image no. 2 for anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 253-267), (C-Term) antibody (ABIN3043979) Anti-Smad1 antibody, Western blotting Lane 1: SMMC Cell Lysate Lane 2: K562 Cell Lysa...
Image no. 3 for anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 253-267), (C-Term) antibody (ABIN3043979) Anti-Smad1 antibody, ICC ICC: A549 Cell
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