PDGFB Antikörper (AA 82-190)

Produktnummer ABIN3043599

Dieser Anti-PDGFB Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PDGFB in WB. Geeignet für Human, Ratte und Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für PDGFB Antikörper (AA 82-190) (ABIN3043599)

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDGFB Antikörper

Bindungsspezifität: AA 82-190

Verwendungszweck: Anti-PDGF beta/PDGFB Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-PDGF beta/PDGFB Antibody (ABIN3043599). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PDGF beta recombinant protein (Position: S82-T190). Human PDGF beta shares 89% amino acid (aa) sequence identity with both mouse and rat PDGF beta.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Referenzen für anti-PDGFB Antikörper (ABIN3043599)

Hong, Hong, Chen, Wang, Hong: "Investigation of the protective effect of erythropoietin on spinal cord injury in rats." in: Experimental and therapeutic medicine, Vol. 2, Issue 5, pp. 837-841, (2012) (PubMed).

Zhao, Wang, Liu, Sun, Kazuhiro: "Protective effects of glutamine in a rat model of endotoxemia." in: Molecular medicine reports, Vol. 6, Issue 4, pp. 739-44, (2012) (PubMed).

Details zu PDGFB

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Andere Bezeichnung: PDGFB

Hintergrund:

Synonyms: Platelet-derived growth factor subunit B,PDGF subunit B,PDGF-2,Platelet-derived growth factor B chain,Platelet-derived growth factor beta polypeptide,Proto-oncogene c-Sis,Becaplermin,PDGFB,PDGF2, SIS,

Tissue Specificity: Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung. .

Background: Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. This gene is mapped to 22q13.1. Growth factor plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. This gene plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.

Sequence Similarities: Belongs to the PDGF/VEGF growth factor family.

Molekulargewicht: 13 kDa

Gen-ID: 5155

UniProt: P01127

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling