Galectin 3 Antikörper (AA 139-250)

Produktnummer ABIN3043399

Produktdetails anti-Galectin 3 Antikörper

Target: Galectin 3 (LGALS3)

Bindungsspezifität: AA 139-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Galectin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Galectin-3(LGALS3) detection. Tested with WB, IHC-P in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Galectin-3(LGALS3) detection. Tested with WB, IHC-P in Human.
Gene Name: lectin, galactoside-binding, soluble, 3
Protein Name: Galectin-3

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Galectin 3 recombinant protein (Position: K139-I250). Human Galectin 3 shares 88% and 84% amino acid (aa) sequences identity with mouse and rat Galectin 3, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Galectin 3 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: LGALS3 (LGALS3 Produkte)

Synonyme: CBP 35 antikoerper, Gal-3 antikoerper, Galectin-3 antikoerper, leg3 antikoerper, galactoside-binding antikoerper, galectin-3 antikoerper, lectin antikoerper, soluble antikoerper, CBP35 antikoerper, GAL3 antikoerper, GALBP antikoerper, GALIG antikoerper, L31 antikoerper, LGALS2 antikoerper, MAC2 antikoerper, MGC52947 antikoerper, MGC75803 antikoerper, LGALS3 antikoerper, gal-3 antikoerper, GBP antikoerper, L-34 antikoerper, Mac-2 antikoerper, gal3 antikoerper, galectin 3 antikoerper, Galectin-3 antikoerper, avian beta-defensin 3 antikoerper, lectin, galactoside-binding, soluble, 3 L homeolog antikoerper, lectin, galactoside-binding, soluble, 3 antikoerper, galectin 2 antikoerper, lectin, galactose binding, soluble 3 antikoerper, LGALS3 antikoerper, leg3 antikoerper, AvBD3 antikoerper, lgals3.L antikoerper, lgals3 antikoerper, LGALS2 antikoerper, Lgals3 antikoerper

Substanzklasse: Chemical

Hintergrund: Galectin-3(GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21-q22. It is expressed in the nucleus, cytoplasm,mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.

Synonyms: 35 kDa lectin antibody|Carbohydrate binding protein 35 antibody|Carbohydrate-binding protein 35 antibody|CBP 35 antibody|CBP35 antibody|GAL 3 antibody|Gal-3 antibody|GAL3 antibody|Galactose specific lectin 3 antibody|Galactose-specific lectin 3 antibody|Galactoside binding protein antibody|Galactoside-binding protein antibody|GALBP antibody|Galectin 3 internal gene,included antibody|Galectin-3 antibody|Galectin3 antibody|GALIG antibody|GBP antibody|IgE binding protein antibody|IgE-binding protein antibody|L 31 antibody|L 34 antibody|L-31 antibody|L-34 galactoside-binding lectin antibody|L31 antibody|Laminin binding protein antibody|Laminin-binding protein antibody|Lectin galactose binding soluble 3 antibody|Lectin galactoside binding soluble 3 antibody|Lectin L 29 antibody|Lectin L-29 antibody|Lectin, galactose binding, soluble 3 antibody|LEG3_HUMAN antibody|LGALS 3 antibody|LGALS2 antibody|LGALS3 antibody|LGALS3 protein antibody|MAC 2 antigen antibody|Mac-2 antibody|Mac-2 antigen antibody|MAC2 antibody|Macrophage galactose-specific lectin antibody|MGC105387 antibody

Gen-ID: 3958

UniProt: P17931

Pathways: RTK Signalweg