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Sonic Hedgehog Antikörper (N-Term)

SHH Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043230
  • Target Alle Sonic Hedgehog (SHH) Antikörper anzeigen
    Sonic Hedgehog (SHH)
    Bindungsspezifität
    • 14
    • 10
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 203-218, N-Term
    Reaktivität
    • 68
    • 48
    • 31
    • 15
    • 9
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 70
    • 12
    • 6
    • 1
    • 1
    Kaninchen
    Klonalität
    • 63
    • 27
    Polyklonal
    Konjugat
    • 50
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Sonic Hedgehog Antikörper ist unkonjugiert
    Applikation
    • 63
    • 29
    • 20
    • 12
    • 12
    • 11
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-Sonic Hedgehog/SHH Antibody Picoband®
    Sequenz
    ATVHLEQGGT KLVKDL
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-Sonic Hedgehog/SHH Antibody (ABIN3043230). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human Sonic Hedgehog, identical to the related rat and mouse sequences.
    Isotyp
    IgG
    Top Product
    Discover our top product SHH Primärantikörper
  • Applikationshinweise
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Tsukurov, O., Boehmer, A., Flynn, J., Nicolai, J.-P., Hamel, B. C. J., Traill, S., Zaleske, D., Mankin, H. J., Yeon, H., Ho, C., Tabin, C., Seidman, J. G., Seidman, C. : A complex bilateral polysyndactyly disease locus maps to chromosome 7q36. Nature Genet. 6: 282-286, 1994.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Dai, Ai, Du, Chen: "Sonic hedgehog expression correlates with distant metastasis in pancreatic adenocarcinoma." in: Pancreas, Vol. 40, Issue 2, pp. 233-6, (2011) (PubMed).

  • Target
    Sonic Hedgehog (SHH)
    Andere Bezeichnung
    SHH (SHH Produkte)
    Hintergrund

    Synonyms: Sonic hedgehog protein,SHH,HHG-1,Sonic hedgehog protein N-product,Sonic hedgehog protein C-product,SHH,

    Tissue Specificity: Expressed in fetal intestine, liver, lung, and kidney. Not expressed in adult tissues.

    Background: The mouse, chicken, and zebrafish Shh homologs are highly conserved. SHH expression was not detected in adult tissues examined. However, it was expressed in fetal intestine, liver, lung, and kidney. SHH gene is mapped to 7q. SHH mutations are not a frequent cause of isolated oral clefts.

    Sequence Similarities: Belongs to the hedgehog family.

    Molekulargewicht
    62-65 kDa
    UniProt
    Q15465
    Pathways
    Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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