Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Sonic Hedgehog Antikörper (N-Term)

Dieses Anti-Sonic Hedgehog-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Sonic Hedgehog in WB und IHC. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN3043230

Kurzübersicht für Sonic Hedgehog Antikörper (N-Term) (ABIN3043230)

Target

Alle Sonic Hedgehog (SHH) Antikörper anzeigen
Sonic Hedgehog (SHH)

Reaktivität

  • 80
  • 56
  • 42
  • 17
  • 10
  • 6
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 84
  • 22
  • 9
  • 1
  • 1
Kaninchen

Klonalität

  • 76
  • 41
Polyklonal

Konjugat

  • 72
  • 10
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Sonic Hedgehog Antikörper ist unkonjugiert

Applikation

  • 89
  • 44
  • 31
  • 19
  • 19
  • 14
  • 13
  • 12
  • 11
  • 10
  • 5
  • 4
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 11
    • 9
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 203-218, N-Term

    Verwendungszweck

    Anti-Sonic Hedgehog/SHH Antibody Picoband®

    Sequenz

    ATVHLEQGGT KLVKDL

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Sonic Hedgehog/SHH Antibody (ABIN3043230). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the N-terminus of human Sonic Hedgehog, identical to the related rat and mouse sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Tsukurov, O., Boehmer, A., Flynn, J., Nicolai, J.-P., Hamel, B. C. J., Traill, S., Zaleske, D., Mankin, H. J., Yeon, H., Ho, C., Tabin, C., Seidman, J. G., Seidman, C. : A complex bilateral polysyndactyly disease locus maps to chromosome 7q36. Nature Genet. 6: 282-286, 1994.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Dai, Ai, Du, Chen: "Sonic hedgehog expression correlates with distant metastasis in pancreatic adenocarcinoma." in: Pancreas, Vol. 40, Issue 2, pp. 233-6, (2011) (PubMed).

  • Target

    Sonic Hedgehog (SHH)

    Andere Bezeichnung

    SHH

    Hintergrund

    Synonyms: Sonic hedgehog protein,SHH,HHG-1,Sonic hedgehog protein N-product,Sonic hedgehog protein C-product,SHH,

    Tissue Specificity: Expressed in fetal intestine, liver, lung, and kidney. Not expressed in adult tissues.

    Background: The mouse, chicken, and zebrafish Shh homologs are highly conserved. SHH expression was not detected in adult tissues examined. However, it was expressed in fetal intestine, liver, lung, and kidney. SHH gene is mapped to 7q. SHH mutations are not a frequent cause of isolated oral clefts.

    Sequence Similarities: Belongs to the hedgehog family.

    Molekulargewicht

    62-65 kDa

    UniProt

    Q15465

    Pathways

    Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Sie sind hier:
Chat with us!