VIPR1 Antikörper (C-Term)

Produktnummer ABIN3043057

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VIPR1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für VIPR1 Antikörper (C-Term) (ABIN3043057)

Target: VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VIPR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-VIPR1 Antikörper

Bindungsspezifität: AA 400-414, C-Term

Verwendungszweck: Anti-VIP Receptor 1/VIPR1 Antibody Picoband®

Sequenz: RRKWRRWHLQ GVLGW

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-VIP Receptor 1/VIPR1 Antibody (ABIN3043057). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human VIP Receptor 1, identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Couvineau, A., Rouyer-Fessard, C., Darmoul, D., Maoret, J.-J., Carrero, I., Ogier-Denis, E., Laburthe, M. Human intestinal VIP receptor: cloning and functional expression of two cDNA encoding proteins with different N-terminal domains. Biochem. Biophys. Res. Commun. 200: 769-776, 1994. 2. Sreedharan, S. P., Huang, J.-X., Cheung, M.-C., Goetzl, E. J. Structure, expression, and chromosomal localization of the type I human vasoactive intestinal peptide receptor gene. Proc. Nat. Acad. Sci. 92: 2939-2943, 1995.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu VIPR1

Target: VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))

Andere Bezeichnung: VIPR1

Hintergrund:

Synonyms: Vasoactive intestinal polypeptide receptor 1,VIP-R-1,Pituitary adenylate cyclase-activating polypeptide type II receptor,PACAP type II receptor,PACAP-R-2,PACAP-R2,VPAC1,VIPR1,

Tissue Specificity: In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T- cell lines Peer, MOLT-4, HSB and YT. .

Background: VIPR1 (Vasoactive intestinal polypeptide receptor 1), also known as VIPR,HVR1, is a protein that in humans is encoded by the VIPR1 gene. Distinct subsets of neural, respiratory, gastrointestinal, and immune cells bear specific high-affinity G protein-coupled receptors for VIP, such as VIPR1. The VIPR1 gene is mapped on 3p22.1. The VIPR1 gene was found to span approximately 22 kb and to be comprised of 13 exons (ranging from 42 to 1,400 bp) and 12 introns (ranging from 0.3 to 6.1 kb). One encodes a VIP receptor consisting of 460 amino acids and having 7 putative transmembrane domains, as do other G protein-coupled receptors. Patients with idiopathic achalasia show a significant difference in the distribution of SNPs affecting VIPR1.

Molekulargewicht: 52 kDa

UniProt: P32241