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RGS14 Antikörper (Regulator of G-Protein Signaling 14) (AA 359-372) Primary Antibody

RGS14 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042860
$240.00
Zzgl. Versandkosten $45.00
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 4 bis 6 Werktagen
  • Target
    RGS14
    Bindungsspezifität
    AA 359-372, C-Term
    • 10
    • 9
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    Reaktivität
    Human, Ratte
    • 54
    • 18
    • 10
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Wirt
    Kaninchen
    • 43
    • 7
    • 4
    • 1
    Klonalität
    Polyklonal
    • 53
    • 2
    Konjugat
    Dieser RGS14 Antikörper ist unkonjugiert
    • 28
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Western Blotting (WB)
    • 47
    • 32
    • 6
    • 3
    • 3
    • 2
    • 1
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    • 1
    • 1
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    Verwendungszweck
    Rabbit IgG polyclonal antibody for Regulator of G-protein signaling 14(RGS14) detection. Tested with WB in Human,Mouse,Rat.
    Sequenz
    CTVLADQEVR LENR
    Kreuzreaktivität (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Regulator of G-protein signaling 14(RGS14) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: regulator of G-protein signaling 14
    Protein Name: Regulator of G-protein signaling 14
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human RGS14(359-372aa CTVLADQEVRLENR), identical to the related mouse and rat sequences.
    Isotyp
    IgG
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Target
    RGS14
    Andere Bezeichnung
    RGS14 (RGS14 Antibody Abstract)
    Synonyme
    RPIP1, MGC80558, RGS14, rgs14, wu:fi04g12, regulator of G protein signaling 14, regulator of G-protein signaling 14, regulator of G-protein signaling 14 L homeolog, regulator of G-protein signalling 14, regulator of G protein signaling 14a, RGS14, Rgs14, rgs14.L, rgs14, rgs14a
    Hintergrund
    Regulator of G-protein signaling 14, also called RGS14, is a protein that in humans is encoded by the RGS14 gene. This gene encodes a member of the regulator of G-protein signaling family. By genomic sequence analysis, this gene is mapped to chromosome 5q35.3. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein(GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

    Synonyms: Highly similar to rap1/rap2 interacting protein antibody|OTTHUMP00000223586 antibody|OTTHUMP00000223587 antibody|Regulation of G protein signaling 14 antibody|Regulator of G protein signaling 14 antibody|Regulator of G protein signalling 14 antibody|Regulator of G-protein signaling 14 antibody|RGS 14 antibody|RGS14 antibody|RGS14_HUMAN antibody
    UniProt
    O43566
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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