KIT Ligand Antikörper (AA 26-190)

Produktnummer ABIN3042808

Produktdetails anti-KIT Ligand Antikörper

Target: KIT Ligand (KITLG)

Bindungsspezifität: AA 26-190

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIT Ligand Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit IgG polyclonal antibody for Kit ligand/Mast cell growth factor(KITLG) detection. Tested with WB, ELISA in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Kit ligand/Mast cell growth factor(KITLG) detection. Tested with WB, ELISA in Human.
Gene Name: KIT ligand
Protein Name: Kit ligand

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human SCF recombinant protein(Position: E26-A190).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Species: Human

Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-KIT Ligand Antikörper (ABIN3042808)

Li, Wu, Miao, Xiong et al.: "Effects of Polysaccharide of Gastrodia Elata Blume and Electro-Acupuncture on Expressions of Brain-Derived Neurotrophic Factor and Stem Cell Factor Protein in Caudate Putamen of Focal Cerebral ..." in: Medical science monitor basic research, Vol. 22, pp. 175-180, (2017) (PubMed).

Jeng, Jeng, Jeng, Sheen, Li, Lu, Chang: "Tropism of liver epithelial cells toward hepatocellular carcinoma in vitro and in vivo with altering gene expression of cancer stem cells." in: American journal of surgery, Vol. 215, Issue 4, pp. 735-743, (2017) (PubMed).

Details zu KIT Ligand

Target: KIT Ligand (KITLG)

Andere Bezeichnung: KITLG (KITLG Produkte)

Synonyme: Xkl-1 antikoerper, Xsl antikoerper, Xsl-1 antikoerper, Xsl-2 antikoerper, steel antikoerper, KITLG antikoerper, SCF antikoerper, kitl antikoerper, kl-1 antikoerper, mgf antikoerper, scf antikoerper, FPH2 antikoerper, KL-1 antikoerper, Kitl antikoerper, MGF antikoerper, SF antikoerper, SHEP7 antikoerper, Clo antikoerper, Con antikoerper, Gb antikoerper, Kitlg antikoerper, Mgf antikoerper, SLF antikoerper, Sl antikoerper, blz antikoerper, contrasted antikoerper, 710-712 antikoerper, CSF antikoerper, KITL antikoerper, KIT ligand L homeolog antikoerper, KIT ligand antikoerper, kit ligand antikoerper, kitlg.L antikoerper, KITLG antikoerper, kitlg antikoerper, Kitl antikoerper, Kitlg antikoerper

Hintergrund: Stem Cell Factor(also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor(CD117). The SCF gene is mapped to 12q21.32. SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis(formation of blood cells), spermatogenesis, and melanogenesis. SCF may be used along with other cytokines to culture HSCs and hematopoietic progenitors. The expansion of these cells ex-vivo(outside the body) would allow advances in bone-marrow transplantation, in which HSCs are transferred to a patient to re-establish blood formation. One of the problems of injecting SCF for therapeutic purposes is that SCF activates mast cells. The injection of SCF has been shown to cause allergic-like symptoms and the proliferation of mast cells and melanocytes.

Synonyms: C kit ligand antibody|C-kit ligand antibody|Ckit ligand antibody|DKFZp686F2250 antibody|familial progressive hyperpigmentation 2 antibody|FPH2 antibody|KIT ligand antibody|Kitl antibody|KITLG antibody|KL 1 antibody|KL1 antibody|Mast cell growth factor antibody|MGF antibody|SCF antibody|SF antibody|SHEP7 antibody|sKITLG antibody|Soluble KIT ligand antibody|Steel factor antibody|Stem cell factor antibody|Stem cell factor precursor antibody

UniProt: P21583

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung