CYLD Antikörper (AA 618-956)

Produktnummer ABIN3042782

Der Kaninchen-Polyklonal Anti-CYLD-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von CYLD in Proben aus Human und Ratte. }

Kurzübersicht für CYLD Antikörper (AA 618-956) (ABIN3042782)

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYLD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CYLD Antikörper

Bindungsspezifität: AA 618-956

Verwendungszweck: Anti-CYLD Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-CYLD Antibody (ABIN3042782). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Andere Bezeichnung: CYLD

Hintergrund:

Synonyms: Ubiquitin carboxyl-terminal hydrolase CYLD,3.4.19.12,Deubiquitinating enzyme CYLD,Ubiquitin thioesterase CYLD,Ubiquitin-specific-processing protease CYLD,CYLD,CYLD1, KIAA0849,HSPC057,

Tissue Specificity: Detected in fetal brain, testis, and skeletal muscle, and at a lower level in adult brain, leukocytes, liver, heart, kidney, spleen, ovary and lung. Isoform 2 is found in all tissues except kidney. .

Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Sequence Similarities: Belongs to the peptidase C19 family.

Molekulargewicht: 107 kDa

Gen-ID: 1540

Pathways: Apoptose, Activation of Innate immune Response