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CRY2 Antikörper (N-Term)

CRY2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042760
  • Target Alle CRY2 Antikörper anzeigen
    CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))
    Bindungsspezifität
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-200, N-Term
    Reaktivität
    • 29
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 24
    • 6
    Kaninchen
    Klonalität
    • 26
    • 4
    Polyklonal
    Konjugat
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CRY2 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 11
    • 9
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-CRY2 Antibody Picoband®
    Sequenz
    RFQAIISRME LPKKPVGLVT SQQMESCRAE
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-CRY2 Antibody Picoband® (ABIN3042760). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human CRY2, different from the related mouse and rat sequences by five amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CRY2 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Kovanen L, Kaunisto M, Donner K, Saarikoski ST, Partonen T. ""CRY2 genetic variants associate with dysthymia."" PLoS One, 2013. 2. Mao Y, Fu A, Hoffman AE, Jacobs DI, Jin M, Chen K, Zhu Y. ""The circadian gene CRY2 is associated with breast cancer aggressiveness possibly via epigenomic modifications."" Tumour Biol, 2015 May.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))
    Andere Bezeichnung
    CRY2 (CRY2 Produkte)
    Hintergrund

    Synonyms: Cryptochrome-2,CRY2,KIAA0658,

    Tissue Specificity: Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle. .

    Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. And it is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

    Sequence Similarities: Belongs to the DNA photolyase class-1 family.

    Molekulargewicht
    67 kDa
    Gen-ID
    1408
    Pathways
    Response to Water Deprivation, Protein targeting to Nucleus
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