SOCS2 Antikörper (AA 96-198)

Produktnummer ABIN3042487

Produktdetails anti-SOCS2 Antikörper

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Bindungsspezifität: AA 96-198

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 2(SOCS2) detection. Tested with WB in Human,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 2(SOCS2) detection. Tested with WB in Human,Rat.
Gene Name: suppressor of cytokine signaling 2
Protein Name: Suppressor of cytokine signaling 2

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SOCS2 recombinant protein (Position: R96-V198). Human SOCS2 shares 96.1% and 95.1% amino acid (aa) sequence identity with mouse and rat SOCS2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat , The detection limit for SOCS2 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu SOCS2

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Andere Bezeichnung: SOCS2 (SOCS2 Produkte)

Synonyme: CIS2 antikoerper, Cish2 antikoerper, SOCS-2 antikoerper, SSI-2 antikoerper, SSI2 antikoerper, STATI2 antikoerper, Cish1 antikoerper, Socs-1 antikoerper, Socs-2 antikoerper, si:dkey-202b22.1 antikoerper, socs2 antikoerper, cis2 antikoerper, ssi2 antikoerper, cish2 antikoerper, ssi-2 antikoerper, socs-2 antikoerper, stati2 antikoerper, 8030460M17 antikoerper, AI527257 antikoerper, AW108012 antikoerper, D130043N08Rik antikoerper, JAB antikoerper, hg antikoerper, Cradd antikoerper, Socs2 antikoerper, suppressor of cytokine signaling 2 antikoerper, suppressor of cytokine signaling 1 antikoerper, death domain-containing protein CRADD antikoerper, suppressor of cytokine signaling 2 S homeolog antikoerper, SOCS2 antikoerper, Socs1 antikoerper, Socs2 antikoerper, socs2 antikoerper, LOC100716104 antikoerper, socs2.S antikoerper

Hintergrund: Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.

Synonyms: CIS 2 antibody|CIS-2 antibody|CIS2 antibody|Cish 2 antibody|Cish2 antibody|Cytokine inducible SH2 protein 2 antibody|Cytokine-inducible SH2 protein 2 antibody|SOCS 2 antibody|SOCS-2 antibody|Socs2 antibody|SOCS2_HUMAN antibody|SSI 2 antibody|SSI-2 antibody|SSI2 antibody|STAT induced STAT inhibitor 2 antibody|STAT-induced STAT inhibitor 2 antibody|STATI 2 antibody|STATI2 antibody|Suppressor of cytokine signaling 2 antibody

Gen-ID: 8835

UniProt: O14508

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus