The antibody GF-01 reacts with GFAP, the principal marker of astroglial cells in the central nervous system, which is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves. The GFAP protein runs on gels at ~55 kDa protein, usually associated with lower Mw bands which are thought to be proteolytic fragments and alternate transcripts from the single gene.
Aufreinigung
Purified from ascites by protein-A affinity chromatography
Immunogen
Pellet of porcine brain cold-stable proteins after depolymerization of microtubules.