RAB8A Antikörper (C-Term)

Produktnummer ABIN3032426

Produktdetails anti-RAB8A Antikörper

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Rab8A (KAKMDKKLEGNSPQ) was used as the immunogen for this Rab8 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Rab8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Rab8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu RAB8A

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Andere Bezeichnung: Rab8 (RAB8A Produkte)

Synonyme: rab8A antikoerper, DDBDRAFT_0206521 antikoerper, DDBDRAFT_0214885 antikoerper, DDB_0206521 antikoerper, DDB_0214885 antikoerper, HSH2D antikoerper, mel antikoerper, rab8 antikoerper, c-mel antikoerper, MEL antikoerper, RAB8 antikoerper, zgc:162699 antikoerper, AA409338 antikoerper, Mel antikoerper, Rab8 antikoerper, rab8A protein antikoerper, Rab GTPase antikoerper, RAB8A, member RAS oncogene family antikoerper, RAB8A, member RAS oncogene family S homeolog antikoerper, rab8A antikoerper, RAB8A antikoerper, rab8a antikoerper, rab8a.S antikoerper, Rab8a antikoerper

Hintergrund: Ras-related protein Rab8 is a protein that in humans is encoded by the RAB8A gene. The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. Rab8 regulates cilia assembly by targeting and promoting fusion of vesicles near the ciliary membrane. This gene requires CEP290 for centrosome localization and that CEP290 regulates entry of Rab8 into the cilium during assembly of this organelle. It has been shown to interact with Optineurin and MAP4K2.

UniProt: P61006

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interaktom