SCO2 Antikörper (C-Term)

Produktnummer ABIN303242

Produktdetails anti-SCO2 Antikörper

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Recognizes SCO Cytochrome Oxidase Deficient Homolog 2 (SCO2).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: SCO2 antibody was raised against Synthetic Peptide (-KLH conjugated) corresponding to 19 Amino Acid peptide from near the carboxy terminus of Human SCO2.

Anwendungsinformationen

Applikationshinweise: Western Blot. Immunohistochemistry on Paraffin Sections (2.5 μg/mL). This SCO2 antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody LS-D1, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

Details zu SCO2

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Andere Bezeichnung: SCO2 (SCO2 Produkte)

Synonyme: CEMCOX1 antikoerper, MYP6 antikoerper, SCO1L antikoerper, SCO cytochrome oxidase deficient homolog 2 (yeast) antikoerper, SCO2 cytochrome c oxidase assembly protein antikoerper, SCO2, cytochrome c oxidase assembly protein antikoerper, SCO2 antikoerper, Sco2 antikoerper

Hintergrund: Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from Cytochrome C to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of Cytochrome C Oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog of the yeast SCO2 gene.Synonyms: Protein SCO2 homolog mitochondrial

Gen-ID: 9997

NCBI Accession: NP_001162580

UniProt: O43819

Pathways: Transition Metal Ion Homeostasis, Warburg Effekt