Prostate Specific Antigen Antikörper (AA 25-261)

Produktnummer ABIN3032350

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Prostate Specific Antigen in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Prostate Specific Antigen Antikörper (AA 25-261) (ABIN3032350)

Target: Prostate Specific Antigen (PSA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prostate Specific Antigen Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Prostate Specific Antigen Antikörper

Bindungsspezifität: AA 25-261

Verwendungszweck: PSA Antibody / Prostate Specific Antigen

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 25-261) was used as the immunogen for this PSA antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the PSA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PSA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: PSA

Hintergrund: Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. It is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. It is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. PSA level is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.

UniProt: P07288

Pathways: Komplementsystem