PLK2 Antikörper (C-Term)

Produktnummer ABIN3032267

Der Kaninchen Polyklonal Anti-PLK2-Antikörper wurde für WB, IHC (p), ICC und FACS validiert. Er ist geeignet, PLK2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PLK2 Antikörper (C-Term) (ABIN3032267)

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-PLK2 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Polo-like kinase 2 (SSELKNRMEYALNMLLQRCN) was used as the immunogen for this PLK2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the PLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the PLK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PLK2

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Andere Bezeichnung: PLK2

Hintergrund: Polo-like kinase 2, also known as SNK, is an enzyme that in humans is encoded by the PLK2 gene. It is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 5. Polo-like kinase 2 is involved in synaptic plasticity, centriole duplication and G1/S phase transition. This gene plays a key role in synaptic plasticity and memory by regulating the Ras and Rap protein signalin: required for overactivity-dependent spine remodeling by phosphorylating the Ras activator RASGRF1 and the Rap inhibitor SIPA1L1 leading to their degradation by the proteasome.

UniProt: Q9NYY3