PLAT Antikörper (AA 366-562)

Produktnummer ABIN3032242

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PLAT in WB. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für PLAT Antikörper (AA 366-562) (ABIN3032242)

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PLAT Antikörper

Bindungsspezifität: AA 366-562

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 366-562) was used as the immunogen for this tPA antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the tPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the tPA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PLAT

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Andere Bezeichnung: tPA

Hintergrund: Tissue Plasminogen activator (tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. tPA is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Gen-ID: 5327

Pathways: Autophagie, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interaktom