MCM5 Antikörper (C-Term)

Produktnummer ABIN3031806

Der Kaninchen Polyklonal anti-MCM5 Antikörper (ABIN3031806) detektiert spezifisch MCM5 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für MCM5 Antikörper (C-Term) (ABIN3031806)

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MCM5 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human MCM5 (EIQHRMQRKVLYRLK) was used as the immunogen for this MCM5 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the MCM5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the MCM5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu MCM5

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Andere Bezeichnung: MCM5

Hintergrund: Minichromosome maintenance, S. cerevisiae, homolog of, 5, also known as CDC46, is a protein that in humans is encoded by the MCM5 gene. The protein is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. And it is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The MCM5 gene contains 16 exons and the encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

UniProt: P33992

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA