IRAK3 Antikörper (C-Term)

Produktnummer ABIN3031495

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IRAK3 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IRAK3 Antikörper (C-Term) (ABIN3031495)

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRAK3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IRAKM Antibody

Sequenz: WFPKYIVPSQ DLRPYKVNID

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human IRAKM (WFPKYIVPSQDLRPYKVNID) was used as the immunogen for this IRAKM antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the IRAKM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the IRAKM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu IRAK3

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Andere Bezeichnung: IRAKM

Hintergrund: Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene. The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma.

UniProt: Q9Y616

Pathways: TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades