Cyclin B1 Antikörper (AA 1-433)

Produktnummer ABIN3030583

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin B1 in WB und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cyclin B1 Antikörper (AA 1-433) (ABIN3030583)

Target: Cyclin B1 (CCNB1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-Cyclin B1 Antikörper

Bindungsspezifität: AA 1-433

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-433) was used as the immunogen for this Cyclin B1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Cyclin B1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Cyclin B1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Cyclin B1

Target: Cyclin B1 (CCNB1)

Andere Bezeichnung: Cyclin B1

Hintergrund: Cyclin B1 is a protein that in humans is encoded by the CCNB1 gene, and it is mapped to 5q13.2. It is a regulatory protein involved in mitosis. The gene product complexes with< a href=../search_result.php?search_txt=cdc2>p34(Cdc2)to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. CCNB1 contributes to the switch-like all or none behavior of the cell in deciding to commit to mitosis. Its activation is well-regulated, and positive feedback loops ensure that once the< a href=../search_result.php?search_txt=cyclin b1>Cyclin B1-< a href=../search_result.php?search_txt=cdk1>Cdk1complex is activated, it is not deactivated.

Gen-ID: 891

Pathways: Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase