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TLR8 Antikörper (C-Term)

This anti-TLR8 antibody (ABIN3029182) is a Rabbit Polyclonal antibody detecting TLR8 in WB. Suitable for Mouse, Rat.
Produktnummer ABIN3029182

Kurzübersicht für TLR8 Antikörper (C-Term) (ABIN3029182)

Target

Alle TLR8 Antikörper anzeigen
TLR8 (Toll-Like Receptor 8 (TLR8))

Reaktivität

  • 85
  • 45
  • 35
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Maus, Ratte

Wirt

  • 81
  • 14
  • 2
  • 1
Kaninchen

Klonalität

  • 83
  • 15
Polyklonal

Konjugat

  • 41
  • 10
  • 9
  • 8
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TLR8 Antikörper ist unkonjugiert

Applikation

  • 72
  • 45
  • 26
  • 15
  • 13
  • 13
  • 11
  • 11
  • 9
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 19
    • 15
    • 10
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Aufreinigung

    Antigen affinity

    Immunogen

    An amino acid sequence from the C-terminus of the rat protein (ENDSRYDNLYIDSIRQY) was used as the immunogen for this TLR8 antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    The stated application concentrations are suggested starting points. Titration of the TLR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Lagerung

    -20 °C

    Informationen zur Lagerung

    After reconstitution, the TLR8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target

    TLR8 (Toll-Like Receptor 8 (TLR8))

    Andere Bezeichnung

    TLR8

    Hintergrund

    Toll-like receptor 8 is a protein that in humans is encoded by the TLR8 gene. It has also been designated as CD288 (cluster of differentiation 288). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognises G-rich oligonucleotides.

    UniProt

    A5H300

    Pathways

    TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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