TLR8 Antikörper (C-Term)

Produktnummer ABIN3029182

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLR8 in WB. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für TLR8 Antikörper (C-Term) (ABIN3029182)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TLR8 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of the rat protein (ENDSRYDNLYIDSIRQY) was used as the immunogen for this TLR8 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the TLR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the TLR8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Andere Bezeichnung: TLR8

Hintergrund: Toll-like receptor 8 is a protein that in humans is encoded by the TLR8 gene. It has also been designated as CD288 (cluster of differentiation 288). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognises G-rich oligonucleotides.

UniProt: A5H300

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades