Cyclin D1 Antikörper (AA 219-238)

Produktnummer ABIN3028596

Dieses Anti-Cyclin D1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cyclin D1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Cyclin D1 Antikörper (AA 219-238) (ABIN3028596)

Target: Cyclin D1 (CCND1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cyclin D1 Antikörper

Bindungsspezifität: AA 219-238

Aufreinigung: Antigen affinity

Immunogen: Amino acids 219-238 (SPNNFLSCYRTTHFLSRVIK) were used as the immunogen for this Cyclin D1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Cyclin D1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Cyclin D1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Cyclin D1

Target: Cyclin D1 (CCND1)

Andere Bezeichnung: Cyclin D1

Hintergrund: D-type cyclins are regarded as essential links between cell environment and the core cell cycle machinery. Cyclin D1, the product of the human gene CCND1, is also known as BCL1. Cyclin D1 expression is regulated by the retinoblastoma protein. Expression of Cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. The CCND1 gene can function as an oncogene.

UniProt: P25322

Pathways: PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, ER-Nucleus Signaling