Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Rekombinanter Keratin Acidic (AE1) Antikörper

AE1 Reaktivität: Human IF, IHC (p) Wirt: Kaninchen Monoclonal RMAK1-1 unconjugated Recombinant Antibody
Produktnummer ABIN3026307
  • Target Alle Keratin Acidic (AE1) Antikörper anzeigen
    Keratin Acidic (AE1)
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 31
    • 11
    • 9
    • 9
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    Human
    Wirt
    • 18
    • 10
    • 3
    Kaninchen
    Klonalität
    • 31
    Monoklonal
    Konjugat
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Unkonjugiert
    Applikation
    • 24
    • 24
    • 23
    • 20
    • 11
    • 3
    • 3
    • 2
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Protein A affinity chromatography
    Immunogen
    An amino acid sequence common to acidic/type I keratins was used as the immunogen for the Acidic Cytokeratin antibody.
    Klon
    RMAK1-1
    Isotyp
    IgG kappa
    Top Product
    Discover our top product AE1 Primärantikörper
  • Applikationshinweise
    Titering of the Acidic Cytokeratin antibody may be required for optimal performance.

    1. This antibody will detect cytokeratins -10, -14, -15, -16, -19.
    2. FFPE testing is enhanced by boiling sections in  pH 6 10  mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.\. Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (2)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store the Acidic Cytokeratin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    Keratin Acidic (AE1)
    Andere Bezeichnung
    Acidic Cytokeratin (AE1 Produkte)
    Hintergrund
    There are two types of cytokeratins/keratins/CKs: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus this specific keratin fingerprint allows the classification of all epithelia upon their keratin expression profile. Furthermore this applies also to the malignant counterparts of the epithelia (carcinomas), as the keratin profile tends to remain constant when an epithelium undergoes malignant transformation. The main clinical implication is that the study of the keratin profile by immunohistochemistry techniques is a tool of immense value widely used for tumor diagnosis and characterization in surgical pathology. [Wiki]
Sie sind hier:
Kundenservice