IFNA2 Antikörper

Produktnummer ABIN3025780

Dieses Anti-IFNA2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IFNA2 in ELISA. Geeignet für Human.

Kurzübersicht für IFNA2 Antikörper (ABIN3025780)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA2 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: N39

Produktdetails anti-IFNA2 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: Purified recombinant human IFNA2 was used as the immunogen for the Interferon alpha 2 antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Interferon alpha 2 antibody should be determined by the researcher.\. ELISA: order BSA/azide-free format for coating

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Interferon alpha 2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu IFNA2

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Andere Bezeichnung: Interferon alpha 2

Hintergrund: Recognizes a protein of 16-27  kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This mAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this mAb is called "site I" and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C