DPP4 Antikörper

Produktnummer ABIN3025647

Der Maus Monoklonal anti-DPP4 Antikörper wird verwendet zum Nachweis von DPP4 in Proben von Human und Ratte. Er wurde validiert für FACS, IF und IHC (fro).

Kurzübersicht für DPP4 Antikörper (ABIN3025647)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DPP4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 202-36

Produktdetails anti-DPP4 Antikörper

Keine Kreuzreaktivität: Schwein, Schaf

Aufreinigung: Protein G affinity chromatography

Immunogen: A human T cell clone was used as the immunogen for the CD26 antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD26 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (Frozen Only): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CD26 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Andere Bezeichnung: CD26

Hintergrund: Recognizes a glycoprotein of 110  kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity