Der Kaninchen Polyklonal anti-DPP4 Antikörper (ABIN302556) detektiert spezifisch DPP4 in IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
This antibody detects Human Dipeptidylpeptidase 4/DPP4 (CD26) at N-terminal domain. BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Immunoaffinity Chromatography
Immunogen
Synthetic 15 amino acid peptide corresponding to the N-terminal domain of Human CD26
Immunohistochemistry on paraffin sections (2.5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
PBS, 0.09 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
Target
DPP4
(Dipeptidyl-Peptidase 4 (DPP4))
Andere Bezeichnung
CD26 / DPP4
Hintergrund
CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein] is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.Synonyms: ADABP, ADCP2, Adenosine deaminase complexing protein 2, DPP IV, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26, TP103