PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
ATG4A
(Autophagy related 4A Cysteine Peptidase (ATG4A))
Andere Bezeichnung
ATG4A
Hintergrund
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.,ATG4A,APG4A,AUTL2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Extracellular Matrix,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Cardiovascular,Heart,ATGs,ATG4A