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CD22 Antikörper (APC)

CD22 Reaktivität: Human FACS Wirt: Maus Monoclonal IS7 APC
Produktnummer ABIN302236
  • Target Alle CD22 Antikörper anzeigen
    CD22 (CD22 Molecule (CD22))
    Reaktivität
    • 144
    • 54
    • 23
    • 5
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 90
    • 64
    • 17
    Maus
    Klonalität
    • 117
    • 55
    • 1
    Monoklonal
    Konjugat
    • 87
    • 15
    • 14
    • 11
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD22 Antikörper ist konjugiert mit APC
    Applikation
    • 105
    • 75
    • 46
    • 39
    • 36
    • 21
    • 13
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Produktmerkmale
    Synonyms: SIGLEC2, Siglec-2, B-cell receptor CD22, Leu-14, BL-CAM, Sialic acid-binding Ig-like lectin 2,B-lymphocyte cell adhesion molecule
    Aufreinigung
    Size-exclusion chromatography
    Immunogen
    Reh human cell line
    Klon
    IS7
    Isotyp
    IgG1
    Top Product
    Discover our top product CD22 Primärantikörper
  • Applikationshinweise
    Flow Cytometry analysis of human blood cells using 10 l reagent / 100 l of whole bloodor 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    CD22 (CD22 Molecule (CD22))
    Andere Bezeichnung
    CD22 (CD22 Produkte)
    Hintergrund
    CD22, also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2,6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs), thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.Synonyms: B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14, SIGLEC2, Sialic acid-binding Ig-like lectin 2, Siglec-2
    UniProt
    P20273
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