TCF4 Antikörper (AA 400-500)

Produktnummer ABIN3021530

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TCF4 in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TCF4 Antikörper (AA 400-500) (ABIN3021530)

Target: TCF4 (Transcription Factor 4 (TCF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-TCF4 Antikörper

Bindungsspezifität: AA 400-500

Sequenz: LRNHAVGPST AMPGGHGDMH GIIGPSHNGA MGGLGSGYGT GLLSANRHSL MVGTHREDGV ALRGSHSLLP NQVPVPQLPV QSATSPDLNP PQDPYRGMPP G

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-500 of human TCF4 (NP_001077431.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Andere Bezeichnung: TCF4

Hintergrund: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.,TCF4,E2-2,FECD3,ITF-2,ITF2,PTHS,SEF-2,SEF2,SEF2-1,SEF2-1A,SEF2-1B,SEF2-1D,TCF-4,bHLHb19,TCF4,Epigenetics & Nuclear Signaling,Transcription Factors,Stem Cells,TCF4

Molekulargewicht: 48-71 kDa

Gen-ID: 6925

UniProt: P15884

Pathways: WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus