S100B Antikörper (AA 1-92)

Produktnummer ABIN3021048

Der Kaninchen Polyklonal Anti-S100B-Antikörper wurde für WB, IHC, IF und IP validiert. Er ist geeignet, S100B in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für S100B Antikörper (AA 1-92) (ABIN3021048)

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-S100B Antikörper

Bindungsspezifität: AA 1-92

Sequenz: MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFE HE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100B (NP_006263.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-S100B Antikörper (ABIN3021048)

Yao, Zhao, Tang, Xiong, Zhao, Liu, Dong, Zou, Cai: "Blockade of β-catenin signaling attenuates toluene diisocyanate-induced experimental asthma." in: Allergy, Vol. 72, Issue 4, pp. 579-589, (2017) (PubMed).

Yao, Zhao, Tang, Liang, Liu, Dong, Zou, Cai: "The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model." in: British journal of pharmacology, Vol. 173, Issue 17, pp. 2600-13, (2017) (PubMed).

Details zu S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Andere Bezeichnung: S100B

Hintergrund: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.,NEF,S100,S100-B,S100beta,S100B,S100 beta,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell differentiation,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,S100B

Molekulargewicht: 10 kDa

Gen-ID: 6285

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine