LIMK2 Antikörper (pThr505)
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- Target Alle LIMK2 Antikörper anzeigen
- LIMK2 (LIM Domain Kinase 2 (LIMK2))
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Bindungsspezifität
- pThr505
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LIMK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Phosphorylated Antibodies
- Immunogen
- A phospho specific peptide corresponding to residues surrounding T505 of human LIMK2
- Isotyp
- IgG
- Top Product
- Discover our top product LIMK2 Primärantikörper
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anti-LIM Domain Kinase 2 (LIMK2) (pSer283) antibody
LIMK2 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2H2-E11 unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (pThr505) antibodyLIMK2 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) antibodyLIMK2 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (Ser283) antibodyLIMK2 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-240) antibodyLIMK2 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 570-599), (C-Term) antibodyLIMK2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB42813 unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-240) antibodyLIMK2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- LIMK2 (LIM Domain Kinase 2 (LIMK2))
- Andere Bezeichnung
- LIMK2 (LIMK2 Produkte)
- Hintergrund
- There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.,LIMK2,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,TGF-b-Smad Signaling Pathway,Protein phosphorylation,LIMK2
- Molekulargewicht
- 69 kDa/72 kDa/77 kDa
- Gen-ID
- 3985
- UniProt
- P53671
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