CD44 Antikörper

Produktnummer ABIN298843

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD44 in FACS, WB, IHC, IHC (p), IP und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Pavian und Green Monkey.

Kurzübersicht für CD44 Antikörper (ABIN298843)

Target: CD44

Reaktivität: Human, Pavian, Green Monkey

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 156-3C11

Produktdetails anti-CD44 Antikörper

Spezifität: Recognizes human CD44, a 90kD type I transmembrane protein which is otherwise known as HCAM or CD44s. Various isoforms of CD44 exist. The 90kD standard form, recognized by this, is expressed on leucocytes, erythrocytes, white matter of the brain and some epithelial cells of the breast and small intestine. Antibodies produced by clone 156-3C11 recognize epitope 3, which is a protease resistant epitope on the CD44 Molecule. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.

Aufreinigung: Affinity purified

Immunogen: Stimulated human leucocytes.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:50 - 1:100), IHC, IHC-Fr (1:100), IHC-P (1:100), IP, WB

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. Western Blot: LS-C58044 detects a band of approximately 80kD in HeLa cell lysates. Immunohistology: This product requires

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Short term: -20°C
Long term: -20°C.

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44

Hintergrund: Name/Gene ID: CD44

Synonyms: CD44, CDW44, CD44 antigen, Cell surface glycoprotein CD44, CSPG8, ECMR-III, Epican, HUTCH-I, LHR, MDU2, MC56, MIC4, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, PGP-I, Pgp1, Phagocytic glycoprotein I, MDU3, CD44R, HCELL, Heparan sulfate proteoglycan

Gen-ID: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling