Serotonin Receptor 3A Antikörper (AA 21-36)

Produktnummer ABIN297638

Der Kaninchen Polyklonal Anti-Serotonin Receptor 3A-Antikörper wurde für WB, IHC und IHC (p) validiert. Er ist geeignet, Serotonin Receptor 3A in Proben von Human und Ratte zu detektieren.

Kurzübersicht für Serotonin Receptor 3A Antikörper (AA 21-36) (ABIN297638)

Target: Serotonin Receptor 3A (HTR3A)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Serotonin Receptor 3A Antikörper

Bindungsspezifität: AA 21-36

Marke: IHC-plus™

Spezifität: In human brain, a 47-50 kD band is observed.

Homologie: Percent identity by BLAST analysis: Rat (100%) Mouse (88%) Hamster (81%).

Aufreinigung: Protein G purified

Immunogen: This antibody was developed by immunizing rabbits with a mixture of synthetic peptides corresponding to amino acids 21-36 (RATQAHSTTQPALLRL) and 421-436 (LSSIRHSLEKRDEMRE) of rat 5-HT3A receptor, GenBank no AAB02949. Percent identity by BLAST analysis: Rat (100%), Mouse (88%), Hamster (81%).

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 μg/mL), WB (1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Andere Bezeichnung: HTR3A / 5-HT3A Receptor

Hintergrund: Name/Gene ID: HTR3A
Subfamily: Serotonin 5-HT3 receptor
Family: Ion channel

Synonyms: HTR3A, 5-HT3-A, 5-HT3R-A, 5-HT3 receptor, 5HT3 serotonin receptor, 5-HT3A, 5-HT3a receptor, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3, 5-HT3R, 5HT3R, HTR3, Serotonin receptor 3A

Gen-ID: 3359

UniProt: P46098

Pathways: Synaptic Membrane