Serotonin Receptor 3A Antikörper (N-Term)

Produktnummer ABIN2792275

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Serotonin Receptor 3A Antikörper wird verwendet zum Nachweis von Serotonin Receptor 3A in Proben von Human, Ratte, Maus, Hund, Rind (Kuh) und Pferd. Er wurde validiert für WB und IHC.

Kurzübersicht für Serotonin Receptor 3A Antikörper (N-Term) (ABIN2792275)

Target: Serotonin Receptor 3A (HTR3A)

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Serotonin Receptor 3A Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: HTR3A Antibody - N-terminal region

Sequenz: LLLPTLLAQG EARRSRNTTR PALLRLSDYL LTNYRKGVRP VRDWRKPTTV

Homologie: Cow: 78%, Dog: 78%, Horse: 91%, Human: 100%, Mouse: 78%, Rat: 78%

Produktmerkmale: This is a rabbit polyclonal antibody against HTR3A. It was validated on Western Blot using a cell lysate as a positive control.

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR3A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Serotonin Receptor 3A Antikörper (ABIN2792275)

Rinaldi, Chiaravalli, Mian, Zucca, Tibiletti, Capella, Bertoni: "Serotonin receptor 3A expression in normal and neoplastic B cells." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 77, Issue 3, pp. 129-35, (2010) (PubMed).

Details zu Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Andere Bezeichnung: HTR3A

Hintergrund:

Background Information: HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Alternative Symbols: HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R

Protein Name: 5-hydroxytryptamine receptor 3A

Molekulargewicht: 55 kDa

Gen-ID: 3359

NCBI Accession: NP_000860

UniProt: P46098

Pathways: Synaptic Membrane