RAGE Antikörper

Produktnummer ABIN285943

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch RAGE in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Säugetier.

Kurzübersicht für RAGE Antikörper (ABIN285943)

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Reaktivität: Säugetier

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser RAGE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-RAGE Antikörper

Spezifität: Specific for Amino acid sequence 385-399 of human receptor for advanced glycated end products.0.1% NaN3

Immunogen: RAGE antibody was raised in goat using a peptide, PKKPPQRLEWKLNTGRTE, as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: >1:260,676, IHC-P: >1:400, WB: >1:3,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu RAGE

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Andere Bezeichnung: RAGE

Hintergrund: The Receptor for Advanced Glycosylated End Products (RAGE) is a member of the immunoglobulin superfamily of cell surface molecules that binds molecules that have been irreversibly modified by non-enzymatic glycation and oxidation, and are know as advanced glycation end products (AGEs). It is expressed by endothelium, mononuclear phagocytes, neurons and smooth muscle cells. Whereas RAGE is present at high levels during development, especially in the central nervous system, its levels decline during maturity.

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine