PDGFRB Antikörper (AA 1013-1025)

Produktnummer ABIN285907

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDGFRB in WB, ICC und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PDGFRB Antikörper (AA 1013-1025) (ABIN285907)

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Produktdetails anti-PDGFRB Antikörper

Bindungsspezifität: AA 1013-1025

Kreuzreaktivität: Maus

Aufreinigung: Protein G affinity chromatography

Immunogen: PDGF receptor beta antibody was raised in rabbit using a synthetic peptide (QPNEGDNDYIIPLA) corresponding to amino acids 1013-1025 of human PDGF receptor beta as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen

Konzentration: Lot specific

Buffer: Frozen in 0.1 M tris-glycine buffer, pH 7.4, with 0.11 NaCl, and 0.05 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C.

Details zu PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Andere Bezeichnung: PDGF Receptor beta

Hintergrund: Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.

Molekulargewicht: 190 kDa (predicted detection band MW)

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling