CD74 Antikörper (N-Term)
Kurzübersicht für CD74 Antikörper (N-Term) (ABIN2856756)
Target
Alle CD74 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Kreuzreaktivität
- Schimpanse
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Kreuzreaktivität (Details)
- Chimpanzee (100 %)
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Produktmerkmale
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Rabbit Polyclonal antibody to CD74 (CD74 Molecule, major histocompatibility complex, class II invariant chain)
CD74 antibody [N1N2], N-term -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CD74. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*
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Kommentare
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Positive Control: Raji , GL261 , Rat2
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.88 mg/mL
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Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Association of variant on the promoter of cluster of differentiation 74 in graves disease and graves ophthalmopathy." in: Bioscience reports, Vol. 40, Issue 8, (2020) (PubMed).
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: "Association of variant on the promoter of cluster of differentiation 74 in graves disease and graves ophthalmopathy." in: Bioscience reports, Vol. 40, Issue 8, (2020) (PubMed).
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- CD74 (HLA-DR-gamma (CD74))
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Andere Bezeichnung
- CD74
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Hintergrund
- Cellular Localization: Membrane, Single-pass type II membrane protein
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Molekulargewicht
- 34 kDa
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Gen-ID
- 972
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Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
Target
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