EVC2 Antikörper (C-Term)

Produktnummer ABIN2856532

Produktdetails anti-EVC2 Antikörper

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EVC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Mouse (85 %)

Produktmerkmale: Rabbit Polyclonal antibody to EVC2 (Ellis van Creveld syndrome 2)
EVC2 antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human EVC2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: A431 , H1299 , HeLa , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu EVC2

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Andere Bezeichnung: EVC2 (EVC2 Produkte)

Synonyme: EVC2 antikoerper, LBN antikoerper, 1110017L09Rik antikoerper, Lbn antikoerper, limbin antikoerper, EvC ciliary complex subunit 2 antikoerper, EVC2 antikoerper, Evc2 antikoerper

Hintergrund: This gene encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants.

Cellular Localization: Membrane, Multi-pass membrane protein

Molekulargewicht: 148 kDa

Gen-ID: 132884

Pathways: Hedgehog Signalweg