PDGFRB Antikörper

Produktnummer ABIN285643

Dieser Schaf Polyklonal Antikörper detektiert spezifisch PDGFRB in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Säugetier.

Kurzübersicht für PDGFRB Antikörper (ABIN285643)

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reaktivität: Säugetier

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser PDGFRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PDGFRB Antikörper

Spezifität: This antibody reacts with bovine albumin by immunoelectrophoresis and ELISA,and may also cross-react with albumin from other species.1 ml@ 1 mg/ml

Aufreinigung: Protein G affinity chromatography

Immunogen: PDGFr antibody was raised in sheep using PDGFr-rDNA expression of the b domain (GST fusion) as the immunogen.

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Purified by protein G chromatography and supplied in PBS with 0.05 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Andere Bezeichnung: PDGFr

Hintergrund: Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling