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Cytokeratin 18 Antikörper

KO Validated KRT18 Reaktivität: Human WB, IF, IHC (p), IP, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856142
  • Target Alle Cytokeratin 18 (KRT18) Antikörper anzeigen
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Reaktivität
    • 243
    • 129
    • 95
    • 42
    • 34
    • 27
    • 22
    • 19
    • 19
    • 18
    • 16
    • 14
    • 14
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    Human
    Wirt
    • 147
    • 128
    • 3
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 146
    • 134
    • 1
    Polyklonal
    Konjugat
    • 147
    • 23
    • 22
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Cytokeratin 18 Antikörper ist unkonjugiert
    Applikation
    • 220
    • 103
    • 85
    • 78
    • 72
    • 55
    • 54
    • 40
    • 37
    • 27
    • 26
    • 19
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Hund, Human, Maus
    Produktmerkmale
    Rabbit polyclonal antibody to Cytokeratin 18 (keratin 18)
    Cytokeratin 18 antibody [N2C2], Internal
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Cytokeratin 18. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product KRT18 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: H1299 , HepG2 , HeLa

    Validation: KO/KD

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.54 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Andere Bezeichnung
    keratin 18 (KRT18 Produkte)
    Hintergrund
    KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Cytoplasm , perinuclear region
    Molekulargewicht
    48 kDa
    Gen-ID
    3875
    UniProt
    P05783
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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