ZEB1 Antikörper
Kurzübersicht für ZEB1 Antikörper (ABIN2856075)
Target
Alle ZEB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
-
-
Kreuzreaktivität
- Human, Maus
-
Produktmerkmale
-
Rabbit Polyclonal antibody to ZEB1 (zinc finger E-box binding homeobox 1)
ZEB1 antibody [N2C1], Internal -
Aufreinigung
- Purified by antigen-affinity chromatography.
-
Immunogen
- Recombinant protein encompassing a sequence within the center region of human ZEB1. The exact sequence is proprietary.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Kommentare
-
Positive Control: 293T , HeLa , HepG2 , Neuro2A , NIH-3T3 , C2C12
Validation: Comparison, KO/KD
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.1 mg/mL
-
Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
-
A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
: "Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer." in: Cancers, Vol. 12, Issue 1, (2019) (PubMed).
: "Estrogen-related receptor alpha induces epithelial-mesenchymal transition through cancer-stromal interactions in endometrial cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 6697, (2019) (PubMed).
: "MiR-206 suppresses epithelial mesenchymal transition by targeting TGF-β signaling in estrogen receptor positive breast cancer cells." in: Oncotarget, Vol. 7, Issue 17, pp. 24537-48, (2017) (PubMed).
: "
-
A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
-
- ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
-
Andere Bezeichnung
- zinc finger E-box binding homeobox 1
-
Hintergrund
-
ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM]
Cellular Localization: Nucleus -
Molekulargewicht
- 124 kDa
-
Gen-ID
- 6935
-
UniProt
- P37275
-
Pathways
- Regulation of Muscle Cell Differentiation
Target
-