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ZEB1 Antikörper

Dieses Anti-ZEB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZEB1 in WB, IF, IP, ICC und ChIP. Geeignet für Human. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.
Produktnummer ABIN2856075

Kurzübersicht für ZEB1 Antikörper (ABIN2856075)

Target

Alle ZEB1 Antikörper anzeigen
ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reaktivität

  • 46
  • 15
  • 9
  • 7
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 33
  • 14
  • 1
Kaninchen

Klonalität

  • 29
  • 19
Polyklonal

Konjugat

  • 44
  • 2
  • 1
  • 1
Dieser ZEB1 Antikörper ist unkonjugiert

Applikation

  • 39
  • 20
  • 18
  • 17
  • 11
  • 9
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)

Güteklasse

KO Validated
  • Kreuzreaktivität

    Human, Maus

    Produktmerkmale

    Rabbit Polyclonal antibody to ZEB1 (zinc finger E-box binding homeobox 1)
    ZEB1 antibody [N2C1], Internal

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human ZEB1. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: 293T , HeLa , HepG2 , Neuro2A , NIH-3T3 , C2C12

    Validation: Comparison, KO/KD

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.1 mg/mL

    Buffer

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Fang, Lin, Liang, Liang: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).

    Huang, Wang, Lo, Tseng, Chen, Wu, Hou, Yuan: "Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer." in: Cancers, Vol. 12, Issue 1, (2019) (PubMed).

    Yoriki, Mori, Kokabu, Matsushima, Umemura, Tarumi, Kitawaki: "Estrogen-related receptor alpha induces epithelial-mesenchymal transition through cancer-stromal interactions in endometrial cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 6697, (2019) (PubMed).

    Yin, Yin, Wang, Zhou, Liu, Yang, Wang, Lu: "MiR-206 suppresses epithelial mesenchymal transition by targeting TGF-β signaling in estrogen receptor positive breast cancer cells." in: Oncotarget, Vol. 7, Issue 17, pp. 24537-48, (2017) (PubMed).

  • Target

    ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

    Andere Bezeichnung

    zinc finger E-box binding homeobox 1

    Hintergrund

    ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM]

    Cellular Localization: Nucleus

    Molekulargewicht

    124 kDa

    Gen-ID

    6935

    UniProt

    P37275

    Pathways

    Regulation of Muscle Cell Differentiation
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