ZEB1 Antikörper
Kurzübersicht für ZEB1 Antikörper (ABIN2856075)
Target
Alle ZEB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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                                            Kreuzreaktivität
- Human, Maus
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                                            Produktmerkmale
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                        Rabbit Polyclonal antibody to ZEB1 (zinc finger E-box binding homeobox 1)
 ZEB1 antibody [N2C1], Internal
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                                            Aufreinigung
- Purified by antigen-affinity chromatography.
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                                            Immunogen
- Recombinant protein encompassing a sequence within the center region of human ZEB1. The exact sequence is proprietary.
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            Kommentare
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                        Positive Control: 293T , HeLa , HepG2 , Neuro2A , NIH-3T3 , C2C12 Validation: Comparison, KO/KD 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Konzentration
- 0.1 mg/mL
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                                            Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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                                            Konservierungsmittel
- ProClin
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                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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                                            : "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling."    in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020)         (PubMed).        
 : "Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer." in: Cancers, Vol. 12, Issue 1, (2019) (PubMed).
 : "Estrogen-related receptor alpha induces epithelial-mesenchymal transition through cancer-stromal interactions in endometrial cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 6697, (2019) (PubMed).
 : "MiR-206 suppresses epithelial mesenchymal transition by targeting TGF-β signaling in estrogen receptor positive breast cancer cells." in: Oncotarget, Vol. 7, Issue 17, pp. 24537-48, (2017) (PubMed).
 
 
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                                            : "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling."    in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020)         (PubMed).        
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    - ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
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                                            Andere Bezeichnung
- zinc finger E-box binding homeobox 1
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                                            Hintergrund
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                        ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM]
 Cellular Localization: Nucleus
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                                            Molekulargewicht
- 124 kDa
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                                            Gen-ID
- 6935
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                                            UniProt
- P37275
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                                            Pathways
- Regulation of Muscle Cell Differentiation
 Target
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