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ORC6 Antikörper (C-Term)

Dieses Anti-ORC6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ORC6 in WB und IHC (p). Geeignet für Human.
Produktnummer ABIN2855901

Kurzübersicht für ORC6 Antikörper (C-Term) (ABIN2855901)

Target

Alle ORC6 Antikörper anzeigen
ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Reaktivität

  • 25
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Human

Wirt

  • 15
  • 7
  • 2
  • 1
Kaninchen

Klonalität

  • 18
  • 7
Polyklonal

Konjugat

  • 25
Dieser ORC6 Antikörper ist unkonjugiert

Applikation

  • 22
  • 9
  • 7
  • 7
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit Polyclonal antibody to ORC6L (origin recognition complex, subunit 6 like (yeast))
    ORC6L antibody [C2C3], C-term

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ORC6. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: Molt-4

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

    Andere Bezeichnung

    origin recognition complex subunit 6

    Hintergrund

    The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

    Cellular Localization: Nucleus

    Molekulargewicht

    28 kDa

    Gen-ID

    23594

    UniProt

    Q9Y5N6

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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