PDK3 Antikörper (Center)
Kurzübersicht für PDK3 Antikörper (Center) (ABIN2855802)
Target
Alle PDK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Center
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Kreuzreaktivität
- Maus, Huhn, Ratte (Rattus), Rind (Kuh), Xenopus tropicalis
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Kreuzreaktivität (Details)
- Mouse (96 %), Chicken (93 %), Rat (96 %), Bovine (98 %), Xenopus tropicalis (83 %)
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Produktmerkmale
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Rabbit Polyclonal antibody to PDK3 (pyruvate dehydrogenase kinase, isozyme 3)
PDK3 antibody [N1C2] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human PDK3. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.4 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
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Andere Bezeichnung
- PDK3
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Hintergrund
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Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Cellular Localization: Mitochondrion matrix -
Molekulargewicht
- 47 kDa
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Gen-ID
- 5165
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Pathways
- PI3K-Akt Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
Target
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