XPA Antikörper (Center)

Produktnummer ABIN2855566

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch XPA in WB, IF, IHC (p), IP und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für XPA Antikörper (Center) (ABIN2855566)

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Produktdetails anti-XPA Antikörper

Bindungsspezifität: Center

Produktmerkmale: Rabbit Polyclonal antibody to XPA (xeroderma pigmentosum, complementation group A)
XPA antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human XPA. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:500-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:500-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: A549

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-XPA Antikörper (ABIN2855566)

Manandhar, Lowery, Boulware, Lin, Lu, Wood: "Transcriptional consequences of XPA disruption in human cell lines." in: DNA repair, Vol. 57, pp. 76-90, (2017) (PubMed).

Details zu XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Andere Bezeichnung: XPA

Hintergrund: This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

Cellular Localization: Nucleus

Molekulargewicht: 31 kDa

Gen-ID: 7507

Pathways: DNA Reparatur