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DCK Antikörper

Dieses Anti-DCK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DCK in WB, IHC, IF, IP, IHC (p) und ICC. Geeignet für Human.
Produktnummer ABIN2855484

Kurzübersicht für DCK Antikörper (ABIN2855484)

Target

Alle DCK Antikörper anzeigen
DCK (Deoxycytidine Kinase (DCK))

Reaktivität

  • 51
  • 27
  • 14
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 38
  • 13
  • 3
Kaninchen

Klonalität

  • 43
  • 11
Polyklonal

Konjugat

  • 36
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DCK Antikörper ist unkonjugiert

Applikation

  • 38
  • 22
  • 21
  • 20
  • 18
  • 11
  • 9
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Güteklasse

KO Validated
  • Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Rabbit Polyclonal antibody to DCK (deoxycytidine kinase)
    DCK antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human DCK. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: PC-12 , Rat2 , A549 , H1299 , 293T , DCK-transfected 293T

    Validation: KO/KD, Overexpression

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.41 mg/mL

    Buffer

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    DCK (Deoxycytidine Kinase (DCK))

    Andere Bezeichnung

    deoxycytidine kinase

    Hintergrund

    Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

    Cellular Localization: Nucleus

    Molekulargewicht

    31 kDa

    Gen-ID

    1633

    UniProt

    P27707
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