PIGA Antikörper

Produktnummer ABIN2855435

Der Kaninchen Polyklonal Anti-PIGA-Antikörper wurde für WB validiert. Er ist geeignet, PIGA in Proben von Human zu detektieren.

Kurzübersicht für PIGA Antikörper (ABIN2855435)

Target: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIGA Antikörper

Kreuzreaktivität: Maus

Produktmerkmale: Rabbit Polyclonal antibody to PIGA (phosphatidylinositol glycan anchor biosynthesis, class A)
PIGA antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PIGA. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: NIH-3T3

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.18 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 1 % BSA, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PIGA

Target: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Andere Bezeichnung: phosphatidylinositol glycan anchor biosynthesis class A

Hintergrund: This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.

Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein

Molekulargewicht: 54 kDa

Gen-ID: 5277

UniProt: P37287

Pathways: Inositol Metabolic Process