ING1 Antikörper (C-Term)

Produktnummer ABIN2855405

Der Kaninchen Polyklonal Anti-ING1-Antikörper wurde für WB validiert. Er ist geeignet, ING1 in Proben von Human zu detektieren.

Kurzübersicht für ING1 Antikörper (C-Term) (ABIN2855405)

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ING1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to ING1 (inhibitor of growth family, member 1)
ING1 antibody [C1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ING1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , HeLa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Andere Bezeichnung: inhibitor of growth family member 1

Hintergrund: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Cellular Localization: Nucleus

Molekulargewicht: 47 kDa

Gen-ID: 3621

UniProt: Q9UK53

Pathways: Protein targeting to Nucleus, Autophagie